Meclizine vs ondansetron

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Meclizine vs ondansetron. Bromphenarimine . BroveX, Dimetane, Lodrane : Carbinoxamine Maleate . Histex Pd, Palgic and Pediatex : Chlorpheniramine (6 days). AHIST, Aller-Chlor, C.P.M, Chlo ...

Ondansetron, Metoclopramide, and Antihistamines Traditional antiemetics have had low rates of success in treating CHS based on reported cases (ondansetron = 1.75%, metoclopramide = 4.35%) [3]. Antihistamines such as dimenhydrinate, diphenhydramine, and meclizine have no studies supporting their use, and the limited …

Meclizine, a long-acting drug with a low side-effect profile, may be ideal in combination with ondansetron for at-risk patients. We randomized 77 subjects scheduled for general anesthesia and screened for 4 of 5 PONV risk factors for experimental or control group assignment. Oct 28, 2019 ... ... ondansetron. This could be given intravenously or by pill. She opts for the intravenous option as her nausea is often debilitating ...Compared with single-dose benzodiazepines, single-dose antihistamines led to a 16.1-point (95% CI, 7.2-25.0) reduction in vertigo symptoms on the 100-point VAS 2 hours posttreatment. However ...Antihistamines resulted in greater patient improvement than benzodiazepines (difference, 16.1) but were not superior to other active comparators, …Drugs with anticholinergic effects may potentiate botulinum toxin effects, which may result in excessive neuromuscular weakness and heighten systemic anticholinergic effects. risperidone. meclizine decreases levels of risperidone by inhibition of GI absorption. Applies only to oral form of both agents.Meclizine can interact with sleep medications, benzodiazepines, and allergy medications like Benadryl. It can also interact with opioids, dronabinol, and alcohol. Most commonly, these interactions can cause more drowsiness. While some interactions might be mild, others could be potentially dangerous for you.The meclizine group had lower VNRS scores in the PACU at 15 (P = .013) and 45 (P = .006) minutes following rescue treatment. The incidence of nausea was lower in the meclizine vs. placebo group ...

Jul 1, 2003 · Am Fam Physician. 2003;68 (1):121-128. Nausea and vomiting of pregnancy, commonly known as “morning sickness,” affects approximately 80 percent of pregnant women. Although several theories ... Lower-cost generic is available. Ratings & Reviews. Nauzene has an average rating of 7.8 out of 10 from a total of 26 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 17% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a ...Ondansetron is an anti-nausea medication and promethazine is a phenothiazine. Side effects of ondansetron and promethazine that are similar include drowsiness and sedation, constipation, and dizziness. Side effects of ondansetron that are different from promethazine include headache, feeling unwell (malaise), fatigue, diarrhea, and abnormal ...Domperidone has an average rating of 9.8 out of 10 from a total of 5 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. Metoclopramide has an average rating of 3.9 out of 10 from a total of 514 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 64% reported a negative ...Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. Dramamine Less Drowsy has an average rating of 9.5 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a ...

Apr 2, 2021 ... Efficacy of dronabinol alone and in combination with ondansetron vs ondansetron alone for delayed chemotherapy-induced nausea and vomiting.Ondansetron orally disintegrating tablet is used to prevent nausea and vomiting caused by certain medical treatments. This medication is available as a generic drug and as the brand-name drug ...Serotonin is a neurotransmitter that also acts as a hormone. About 90% of your serotonin is in the cells that line your gastrointestinal tract. Serotonin has several roles, including regulating your mood, digestion, sleep and more. Nausea happens when your body releases serotonin into your gut faster than it can digest it.Lower-cost generic is available. Ratings & Reviews. Nauzene has an average rating of 7.8 out of 10 from a total of 26 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 17% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a ...

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When you're searching for an elusive award, consider letting someone else do the work. Update: Some offers mentioned below are no longer available. View the current offers here. Fo...Bonine (meclizine) and Dramamine (dimenhydrinate) are antihistamines used to treat and prevent motion sickness. While similar, both medications contain key differences, including their active ingredients and dosing guidelines. Read on for an in-depth comparison of Bonine and Dramamine.Meclizine for Dogs. $13.40. Buy on Amazon. Meclizine is an over-the-counter medication that can be easily purchased from an online pharmacy or a regular drug store. Remember that the dosages for humans are different from that of dogs - so be sure to consult with a veterinarian if you are unsure of the dosage.Gastroenteritis. Acute gastroenteritis is caused by viral, bacterial or protozoal infections. Therapeutic options available for adults with vomiting secondary to gastroenteritis include dopamine antagonists such as metoclopramide or prochlorperazine and serotonin antagonists such as ondansetron.15 Nausea and vomiting resulting from acute gastroenteritis is particularly challenging in children.While the first clinical comparison of SENS-111 with the H 1 antihistamine meclizine was recently completed confirming that it does not impact vigilance or cognitive performance (unpublished data), with the AUV clinical trial still ongoing, SENS-111 efficacy vs other antihistamines in patients is awaited. Studies of vestibular modulation by ...

There are 280 drugs known to interact with Meclicot (meclizine), along with 4 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 9 are major, 269 are moderate, and 2 are minor. ... Zofran (ondansetron) Meclicot alcohol/food interactions. There is 1 alcohol/food interaction with Meclicot (meclizine).Meclizine is the most common outpatient medication. This medication is indicated for vertigo but should not be given for other categories of dizziness (near …Ondansetron reduces nausea and vomiting in children with acute gastroenteritis and in women with hyperemesis gravidarum. ... Antihistamines such as meclizine (Antivert) and scopolamine are ...Neurokinin-1 (NK-1) receptor antagonists are antiemetic drugs with unique anxiolytic, antidepressant, and antiemetic properties. The discovery of NK-1 receptor blockers was crucial in preventing emesis associated with cancer chemotherapy. The NK-1 receptor antagonist competitively binds to the NK-1 receptor, thereby blocking the binding of substance P and preventing the transmission of the ...Antihistamines that are commonly used for nausea include cyclizine, chlorcyclizine, diphenhydramine, dimenhydrinate, doxylamine, meclizine, hydroxyzine and promethazine. The anticholinergics also have antiemetic activity, although their other side effects often outweigh any relief they might provide for nausea.Serotonin-receptor antagonists: Ondansetron, granisetron, dolasetron, palonosetron. The mechanism of action is to block serotonin from interacting with the 5-HT3 receptor. ... Diphenhydramine, meclizine, promethazine are common medications in this class. They are widely available, generally well-tolerated, and PO, IV, IM, PR …Comparing Nausea Control vs Ondansetron. Nausea Control (phosphorated carbohydrate solution) Ondansetron. Over-the-counter. Prescribed for Nausea/Vomiting. Nausea Control may also be used for purposes not listed in this medication guide. Prescription only. Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may ...Although meclizine and promethazine also display antiemetic activity, administration of antiemetic compounds (such as ondansetron, an antagonist of the 5-HT3 receptors, or metoclopramide, a dopaminergic antagonist) could be proposed to reduce the neuro-vegetative symptoms accompanying AUV. These drugs could be generally administered per os ...Emetrol has an average rating of 8.5 out of 10 from a total of 50 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 10% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 16% reported a negative effect.Nonsedating antihistamines, ondansetron, and ginger root are not effective in the prevention and treatment of motion sickness. ... (Marezine), dimenhydrinate, promethazine, and meclizine (Antivert ...

ZOFRAN ODT orally disintegrating tablets are white, round, and plano-convex tablets available in the following strengths: 4 mg - debossed with “Z4” on one side. 8 mg - debossed with “Z8” on one side. ZOFRAN oral solution, 4 mg/5 mL, is a clear, colorless to light yellow liquid with a characteristic strawberry odor available in a 50-mL ...

Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. Risk factors for PONV and PDNV. By identifying risk factors for PONV, we can ensure that those patients who are the most in need and stand to gain the greatest benefit receive optimal antiemetic prophylaxis 21- 26.A number of factors, including patient-, anesthetic-, and surgical-related factors, influence the occurence of postoperative emetic symptoms ( Table 1 - Table 3) 27, 28. Compare Meclizine vs Ondansetron head-to-head with other drugs for uses, ratings, cost, side effects and interactions. o Ondansetron (Zofran®) Dosage: 0.5-1 mg/kg orally up to three times a day, or 4 mg for a small dog and 8 mg for a large dog. Indication/s: This can also be an expensive medication. However, it is a great first-line or second-line treatment for dogs with mild to severe inappetence, nausea or vomiting. Ondansetron can come in a dissolvable ...Zofran. A total of 347 drugs are known to interact with Zofran . Zofran is in the drug class 5HT3 receptor antagonists . Zofran is used to treat the following conditions: Nausea/Vomiting. Nausea/Vomiting, Chemotherapy Induced. Nausea/Vomiting, Postoperative. Nausea/Vomiting, Radiation Induced.Meclizine is a medication that has been used to treat nausea and vomiting, motion sickness, and vertigo (a feeling of whirling and loss of balance). It belongs to a class of medications called antihistamines. Meclizine is available over-the-counter and by prescription. Some brand names that can include meclizine are Antivert Ò, Bonine Ò ...Pharmacodynamics. Ondansetron is a highly specific and selective serotonin 5-HT 3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors Label, 3,4.The serotonin 5-HT 3 receptors are located on the nerve terminals of the vagus in the periphery, and centrally in the chemoreceptor trigger zone of the area postrema Label, 3,4.We compare the side effects and drug effectiveness of Zofran odt and Meclizine hydrochloride. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 139,955 people who take Zofran odt and Meclizine hydrochloride, and is updated regularly. You can use the study as a second opinion to make health ...

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Ondansetron Interactions. There are 347 drugs known to interact with ondansetron, along with 2 disease interactions. Of the total drug interactions, 126 are major, 216 are moderate, and 5 are minor. Does ondansetron interact with my other drugs? Enter other medications to view a detailed report. ...These include ondansetron and promethazine and meclizine. Ondansetron (Zofran) Ondansetron, used alone or with other medications, is often prescribed to patients undergoing cancer drug treatment (chemotherapy) and radiation therapy. Ondansetron and its related medications are used to treat nausea and vomiting. Mode of actionSingle-dose aprepitant vs ondansetron for the prevention of postoperative nausea and vomiting: a randomized, double-blind phase III trial in patients undergoing open abdominal surgery. ... meclizine, cyclizine, and hydroxyzine have all been used effectively in the treatment of PONV. Promethazine also has significant antihistamine properties ...Domperidone has an average rating of 9.8 out of 10 from a total of 5 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. Ondansetron has an average rating of 7.7 out of 10 from a total of 487 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 19% reported a negative …Meclizine Pregnancy Warnings. Animal studies have shown cleft palates at 25 to 50 times the human dose. However, epidemiological studies in pregnant women do not indicate this drug increases the risk of abnormalities when administered during pregnancy. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to ...Postoperative nausea and vomiting (PONV) is a common occurrence following anesthesia and leads to patient dissatisfaction and discomfort. In certain settings, PONV can lead to postoperative complications especially in a patient that cannot tolerate elevated heart rate or blood pressure, intrathoracic pressure, or central venous pressure. Resources report that frequency of PONV is up to 80% in ...The "Hulu of movies" is coming for Verizon customers, Twitter emphasizes search, and Google hits back at Apple's decision to refuse Google Voice on the iPhone (okay, not really). T...Apr 10, 2021 ... other, versus no treatment, or versus ... and meclizine. 3.4.2. Serious adverse events ... and ondansetron) and two with moderate certainty evidence ...Metoclopramide may be used short-term for the treatment of gastrointestinal reflux disease that is unresponsive to other medications or to treat diabetic stasis. Side effects may include sedation... more. Prescription only. Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with ...While the first clinical comparison of SENS‐111 with the H 1 antihistamine meclizine was recently completed confirming that it does not impact vigilance or cognitive performance (unpublished data), with the AUV clinical trial still ongoing, SENS‐111 efficacy vs other antihistamines in patients is awaited. Studies of vestibular modulation by ...Jul 11, 2021 ... ... meclizine, dimenhydrinate, ondansetron, scopolamine, proton pump inhibitors, omeprazole, esomeprazole, lansoprazole, pantoprazole ... ….

Meclizine is a prescription drug that comes as an oral tablet. It also comes as a chewable tablet. Meclizine oral tablet is a prescription drug that’s available as the brand-named drug Antivert ...Meclizine is the most common outpatient medication. This medication is indicated for vertigo but should not be given for other categories of dizziness (near-syncope, dysequilibrium, or lightheadedness). ... Ondansetron selective 5-HT3 receptor antagonist; binds to 5-HT3 receptors both in periphery and in CNS, with primary effects in GI tract ...These findings are in agreement with other studies, where ondansetron was more effective in the prevention of vomiting than of nausea. After gynecologic surgery, ondansetron 8 mg was found to reduce the incidence of vomiting to 13%, in comparison to 45% after droperidol 1.25 mg, whereas the incidence of nausea was not influenced [10].Mean (SD) time to eye opening was significantly prolonged in the cyclizine group [10 (4) min vs. 8 (2) min; p < 0.001], but this had no influence on discharge times. Cyclizine and ondansetron appear equally effective in preventing postoperative nausea and vomiting but the 10-fold price differential favours cyclizine.Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness. 9, 10, 11 Dimenhydrinate is a combination of Diphenhydramine and 8-chlorotheophylline in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8 ...Vertigo, a type of dizziness, is the illusion of motion, usually rotational motion. Associated symptoms include nausea, emesis, and diaphoresis. Vertigo should be distinguished from other types of ...The available pharmacokinetic information for meclizine following oral administration has been summarized from published literature. Absorption . Meclizine is absorbed after oral administration with maximum plasma concentrations reaching at a median T max value of 3 hours post-dose (range: 1.5 to 6 hours) for the tablet dosage form. DistributionVertigo is the perception of motion in the absence of movement, which may be described as a sensation of swaying, tilting, spinning, or feeling unbalanced. Due to highly variable descriptions of vertigo, it is often consolidated into the umbrella descriptor 'dizziness', a very common but imprecise complaint that accounts for over three million emergency department (ED) visits annually.[1 ...While the first clinical comparison of SENS-111 with the H 1 antihistamine meclizine was recently completed confirming that it does not impact vigilance or cognitive performance (unpublished data), with the AUV clinical trial still ongoing, SENS-111 efficacy vs other antihistamines in patients is awaited. Studies of vestibular modulation by ...August 17, 2020 by Josh Farkas. CONTENTS. Rapid Reference. Differential diagnosis of nausea and vomiting. Evaluation. Treatment. Pharmacological fundamentals. 5HT3 … Meclizine vs ondansetron, Further, side effects associated with AT would make it difficult to blind patients to the drug vs. placebo, which may skew the results of RCTs in favor of a response to AT. 3.2. Recommendation 2. We conditionally recommend that adults with moderate‐to‐severe CVS receive topiramate as an alternate prophylactic medication ..., Antihistamines include meclizine (Antivert®), dimenhydrinate, diphenhydramine (Benadryl®) and promethazine. These drugs can prevent motion sickness and reduce the severity of symptoms even if taken after the onset of symptoms 5. Dry mouth and blurry vision are side effects that result from their anticholinergic action. Anticholinergics , A few OTC treatments are available that can be helpful in relieving nausea, vomiting, and dizziness. Dimenhydrinate (Dramamine) and meclizine (Bonine) are perennial favorites for treating symptoms associated with motion sickness. Emetrol (consisting of dextrose, fructose, and phosphoric acid), can be effective in treating nausea., Amitriptyline, beta blockers, calcium channel blockers, acetazolamide, and topiramate are commonly used in the prevention of migraine headaches 14 and are also used for vestibular symptoms in migraineurs. 17 Migraine prophylactic medications are used by some centers for Ménière’s disease but controlled studies are lacking. Therapeutic ..., Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. Scopolamine has an average rating of 5.6 out of 10 from a total of 207 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 38% reported a negative …, Absorption. Most histamine H1 antagonists are reported to be readily absorbed following oral administration. 4 Upon oral administration, the time to reach peak plasma concentrations (Cmax) of meclizine is about 3 hours post-dose, with the value ranging from 1.5 to 6 hours. 6 Volume of distribution. The volume of distribution of meclizine in humans has not been fully studied., Key takeaways: Several medications can help with nausea from motion sickness. They work best when taken ahead of time to prevent symptoms from happening in the first place. Options include prescription scopolamine patches (Transderm Scop) and over-the-counter antihistamine pills, like dimenhydrinate (Dramamine) and meclizine (Bonine)., Pharmacodynamics. Ondansetron is a highly specific and selective serotonin 5-HT 3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors Label, 3,4.The serotonin 5-HT 3 receptors are located on the nerve terminals of the vagus in the periphery, and centrally in the chemoreceptor trigger zone of the area postrema Label, 3,4., Summary: Drug interactions are reported among people who take Zofran and Dramamine. Common interactions among females include acute pulmonary oedema and drug toxicity. Common interactions among males include cerebellar ataxia and drug dependence. The phase IV clinical study analyzes what interactions people have when they take Zofran and ..., More about Ondansetron. Ratings & Reviews. Lorazepam has an average rating of 8.0 out of 10 from a total of 1050 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 13% reported a negative effect. Ondansetron has an average rating of 7.7 out of 10 from a total of 487 ratings on Drugs.com. 73% of reviewers reported a ..., Ondansetron is the most often recommended antiemetic but has been shown to be a poor treatment choice for motion sickness. [34, 35] Benzodiazepines such as diazepam have been shown to prevent motion sickness but not as well as other options. ... 2010antivert-bonine-meclizine-343062Drugs. Drugs ..., Mar 31, 2022 ... Antivert (meclizine). What are antiemetics ... and chemotherapy-induced nausea and vomiting (CINV) in adults and children. ... (ondansetron), Anzemet ..., Ondansetron has an average rating of 7.7 out of 10 from a total of 487 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 19% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 16% reported a negative …, More about Dramamine (dimenhydrinate) More about Ondansetron Ratings & Reviews: Dramamine has an average rating of 8.9 out of 10 from a total of 53 ratings on Drugs.com. 87% of reviewers reported a positive effect, while 8% reported a negative effect. , Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (dizziness or lightheadedness) caused by ear problems. Meclizine is an antihistamine. It works to block the signals to the brain that cause nausea, vomiting, and dizziness. This medicine is available only with your ..., The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ..., Descriptions. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting., More about Zofran ( ondansetron ) Ratings & Reviews. Bonine has an average rating of 8.4 out of 10 from a total of 49 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 14% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a ..., Meclizine, a long-acting drug with a low side-effect profile, may be ideal in combination with ondansetron for at-risk patients. We randomized 77 subjects scheduled for general anesthesia and screened for 4 of 5 PONV risk factors for experimental or control group assignment., Meclizine is a medication that has been used to treat nausea and vomiting, motion sickness, and vertigo (a feeling of whirling and loss of balance). It belongs to a class of medications called antihistamines. Meclizine is available over-the-counter and by prescription. Some brand names that can include meclizine are Antivert Ò, Bonine Ò ..., Summary: We compare the side effects and drug effectiveness of Compazine and Meclizine hydrochloride from 64,592 people who take the 2 drugs. The phase IV clinical study is created by eHealthMe based on reports of people who take Compazine and/or Meclizine hydrochloride from sources including the FDA, and is updated regularly., Phenothiazine antiemetics are a type of medicine that may be used to relieve nausea and vomiting.They work by inhibiting dopamine, muscarinic and histamine (H1) receptors generally in the vomiting center and chemoreceptor trigger zone., Stick your nose to the window. Motion sickness happens when the motion your ear detects doesn't match the motion your eyes see. Completely useless at night though. The mammalian diving reflex. When our faces get wet and we hold our breath (or gasp), it triggers the mammalian diving reflex., Summary: Drug interactions are reported among people who take Magnesium and Meclizine. Common interactions among females include pain and dyspnoea. Common interactions among males include arthralgia and cardiac failure congestive. The phase IV clinical study analyzes what interactions people have when they take Magnesium and Meclizine together., Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking meclizine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination., Ondansetron has an average rating of 7.7 out of 10 from a total of 487 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 19% reported a negative effect. Promethazine has an average rating of 7.3 out of 10 from a total of 380 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative ..., Meclizine is an antihistamine that is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It may also be used to reduce dizziness and loss of balance (vertigo ..., Compared with single-dose benzodiazepines, single-dose antihistamines led to a 16.1-point (95% CI, 7.2-25.0) reduction in vertigo symptoms on the 100-point VAS 2 hours posttreatment. However ..., August 22, 2022. Antihistamines provided greater relief for patients with acute vertigo than benzodiazepines, however, other medications yielded similar results as antihistamines, …, Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (dizziness or lightheadedness) caused by ear problems. Meclizine is an antihistamine. It works to block the signals to the brain that cause nausea, vomiting, and dizziness. This medicine is available only with your ..., More about Promethazine. Ratings & Reviews. Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. Promethazine has an average rating of 7.3 out of 10 from a total of 380 ratings on Drugs.com. 65% of reviewers reported a ..., Patients in the early stage of vestibular neuritis who received ondansetron were found to have better vestibular function than those who received metoclopramide, indicating a possible protective effect (Venail et al, 2012). If that is the case, patients should be allowed to keep taking ondansetron during testing. Second-Generation Antihistamines, Ondansetron is a generic prescription drug. It's FDA-approved to help prevent nausea and vomiting in certain situations. Specifically, the drug is prescribed for: adults receiving chemotherapy ...