Lisinopril reviews

Consumer ratings and reviews for LISINOPRIL (LISINOPRIL) (page 2). Includes 454 patient ratings with average score of 1.5, comments, side effects, dosage, sex, age, time taken.

Lisinopril reviews. Lisinopril is a prescription drug used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors that relax the blood vessels and lower the blood pressure. Learn about its side effects, interactions, warnings, and alternatives.

In short, you may experience ED or other sexual issues when you first start using lisinopril, but research suggests that this isn’t a long-term issue. In general, angiotensin-converting enzyme (ACE) inhibitors — the class of medications to which lisinopril belongs — are among the cardiovascular medications least likely to cause ED ...

ACE inhibitors are medications used to treat and manage hypertension, which is a significant risk factor for coronary disease, heart failure, stroke, and a host of other cardiovascular conditions. Most cases are primary and not attributable to any specific etiology. This activity reviews the indications, contraindications, activity, adverse events, and other key elements of ACE inhibitor ...Key points. Most blood pressure medications, including lisinopril and metoprolol succinate, can cause fatigue, low energy, dizziness, and headache. These side effects tend to get less severe over time. Metoprolol succinate specifically, is more strongly associated with sedation and fatigue when compared to many other beta-blockers and …However the consumer should be informed about these side effects to protect himself in any possible complication. The most common prinivil (lisinopril) side effects are: headache, dizziness, diarrhea, drowsiness, cough. The below side effects can occur but less: difficult breathing, nausea, vomiting, fever, stuffy nose, fatigue, taste changes ...Three people share their experiences of taking lisinopril (Zestril), a medication that lowers blood pressure and treats heart failure. Learn about the benefits, …Oct 25, 2016 · Lisinopril (Zestril) received an overall rating of 5 out of 10 stars from 219 reviews. See what others have said about Lisinopril (Zestril), including the effectiveness, ease of use and side effects.

Most voted positive review. 72 People found this comment helpful . BP was 186/92 then Dr. prescribed 20mg Lisinopril & I quickly developed blurred vision, headaches, tiredness and a nagging dry cough.First Name. Last Name. Sildenafil, Viagra, in particular, comes in 25, 50, and 100 mg doses. In general, the most prescribed beginner's dose is 50 mg. Now you can get generic (no brand) sildenafil tablets that work exactly the same way. Sildenafil is available in 25mg, 50mg and 100mg tablets.Lisinopril is an angiotensin converting enzyme inhibitor (ACE-I) that has been on market for more than 25 years. ACE-I are usually well tolerated and rarely have serious or life-threatening side effects. ... Mayo Clinic Gastroenterology and Hepatology Board Review. 3rd ed. Rochester, MN: Mayo Foundation for Medical Education and …Lisinopril is a white to off-white, crystalline powder, with a molecular weight of 441.53. It is soluble in water and sparingly soluble in methanol and practically insoluble in ethanol. Lisinopril is supplied as 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg and 40 mg tablets for oral administration. Inactive Ingredients:Feb 29, 2024 · kidney problems - swelling, urinating less, feeling tired or short of breath; or. liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common lisinopril side effects may include: headache, dizziness; Lisinopril Side Effects Can Be Life Threatening: A lisinopril cough can ruin the quality of your life. It can disrupt sleep and lead to lots of other complications. It is rarely lethal. A far more worrisome lisinopril side effect is called angioedema. It can be life threatening.Read comments and ratings on the side effects, benefits, and effectiveness of lisinopril oral, a medication for high blood pressure. See how other patients experienced cough, …

Zestril (lisinopril) is a brand-name prescription drug that’s used for certain conditions, including high blood pressure. Learn about side effects and more.Lisinopril tablets, USP, are indicated to reduce signs and symptoms of systolic heart failure [see Clinical Studies (14.2)]. 1.3 Reduction of Mortality in Acute Myocardial Infarction Lisinopril tablets, USP, are indicated for the reduction of mortality in treatment of hemodynamically stable patients within 24 hours of acute myocardial infarction. Lisinopril User Reviews & Ratings (Page 2) Brand names: Zestril, Prinivil, Qbrelis. Lisinopril has an average rating of 5.1 out of 10 from a total of 615 reviews on Drugs.com. 34% of reviewers reported a positive experience, while 43% reported a negative experience. Find 4307 user ratings and reviews for Lisinopril Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Condition: High Blood Pressure. Overall rating 2.0. Effectiveness. Ease of Use. Satisfaction. I am a busy author, aged 81, and also run an air bnb business out of my home. In November 2023 I was prescribed 10mg of Lisinopril for high bp. At the end of December I slipped and fell from my loft ladder and hurt my back.

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Depending on your symptoms and needs, you may be prescribed Viagra, sildenafil, Cialis, tadalafil, Stendra, paroxetine, or a combination of tadalafil and sildenafil, available as mints or pills. Prices range from $3 to $139 per dose or $82 to $958 for a monthly supply, depending on the medication.Key takeaways: Lisinopril is a common treatment option for high blood pressure. It also has many other benefits — like improving survival after a heart attack. Lisinopril works by blocking the production of a hormone called angiotensin II. This relaxes blood vessels and lowers blood pressure.In today’s digital age, customer reviews have become a powerful tool that can make or break a business. More and more consumers are turning to online platforms to research and eval...burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. feeling of constant movement of self or surroundings. heartburn. indigestion. muscle cramps. sensation of spinning. stomach discomfort or upset. swelling. Other side effects not listed may also occur in some patients.

Lisinopril works by blocking a substance in the body that causes the blood vessels to tighten. As a result, lisinopril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Lisinopril is also used to help treat heart failure. It is also used in some patients after a heart attack.Read user reviews of lisinopril, a blood pressure medication that some people report helps with migraines. See ratings, success stories, side effects and frequently asked questions.Blurred vision, sweating, urine changes, and increases in creatinine and potassium may also occur. Rarely, lisinopril may adversely affect kidney function. Monitoring of kidney function and potassium levels should occur periodically in those receiving lisinopril. Allergic reactions, including angioedema (swelling of airways and facial areas ...But lisinopril 20 mg decreased systolic blood pressure by about 14 points, and lisinopril 80 mg decreased it by about 20 points. Besides this small study, most of the available research we have is on lisinopril 10 mg. Research indicates that lisinopril 10 mg once daily may decrease your systolic blood pressure by about 8 points.Nov 4, 2022 · Lisinopril is a medication often used to treat high blood pressure. It does not commonly cause erectile dysfunction (ED). When ED is caused by high blood pressure, taking lisinopril to treat HBP can actually help to improve ED symptoms. In the rare case that lisinopril may cause new ED, it usually settles within a month of starting treatment. Jan 17, 2023 · Lisinopril in paediatric medicine: a retrospective chart review of long-term treatment in children., Raes A,Malfait F,Van Aken S,France A,Donckerwolcke R,Vande Walle J,, Journal of the renin-angiotensin-aldosterone system : JRAAS, 2007 Mar [PubMed PMID: 17487821] Lisinopril (brand: Zestril or Prinivil) is an ACE inhibitor that works to reduce blood pressure. It primarily works through the kidneys, so people with renal problems might not be able to take it. For everyone else though, it works effectively and doesn't cause the lethargy common to beta-blockers (like metoprolol or atenolol). ...Review of side effects in the sample. As expected, the higher dose of the medication produced more side effects or 11 (5.9%) in a group of patients on Lisinopril/hydrochlorothiazide a 20 mg, compared to one (1.2%) patient in a group of Lisinopril/hydrochlorothiazide a 10 mg. This difference cannot be considered as …High blood pressure, or hypertension, affects millions of people worldwide. If left untreated, it can lead to serious health complications, such as heart disease and stroke. Therefore, it is crucial to manage blood pressure effectively. Two commonly prescribed medications for this purpose are Lisinopril and Losartan. In this article, we will explore these two drugs, …Lisinopril is an ACE inhibitor used to treat hypertension, heart failure, and heart attack. It can cause serious side effects, such as kidney problems, low blood pressure, and allergic reactions. Learn about …High blood pressure, or hypertension, affects millions of people worldwide. If left untreated, it can lead to serious health complications, such as heart disease and stroke. Therefore, it is crucial to manage blood pressure effectively. Two commonly prescribed medications for this purpose are Lisinopril and Losartan. In this article, we will explore these two drugs, …

It has been underlined that the lisinopril-mediated anti-oxidative effect might be related to the activation of prostacyclin synthesis (Li et al., 2021). In addition, lisinopril has been shown to upregulate constitutive e-NOS via an increase in bradykinin (Ancion et al., 2019) or downgrade lipid peroxidation (Silva et al., 2020).

In can you take cbd gummies with lisinopril May 1965, ... Lin Yutang s materials one by one, and he ordered them to gummies hear Fujianese all day botanical …Condition: High Blood Pressure. Overall rating 3.3. Effectiveness. Ease of Use. Satisfaction. Took Losartan for about a year, it lowered my pressure a little but nothing major. I got horrible side effects, stuffy nose, dizzy, sleepy, joint pain, nervous, raised pulse, poor sleep.These common side effects of lisinopril happen in more than 1 in 100 people. Talk to your doctor or pharmacist if these side effects bother you or do not go away: A dry, tickly cough that does not get better. Feeling dizzy or lightheaded, especially when you stand up or sit up quickly. Headaches. Being sick (vomiting)In today’s digital age, finding a reputable hair stylist can be a daunting task. With so many options available, it can be overwhelming to choose the right one. This is where revie...When taken as prescribed, lisinopril can start lowering blood pressure within an hour, decreasing the systolic (upper) pressure by as much as 26.7 mm Hg and diastolic (lower) pressure by as much as 10.2 mm Hg, depending on the dosage. Higher doses may deliver greater decreases in blood pressure, but they can also increase the risk of side effects.Lisinopril or Zestril is a medication used to treat high blood pressure and heart failure. Learn which lisinopril side effects are common and which are serious. ... According to a 2023 review in ...Lisinopril is classified as an angiotensin-converting enzyme inhibitor and has been available for nearly three decades. Lisinopril has some key features that make it different from enalapril and captopril; 1) it has a long half-life, 2) it is hydrophilic, and 3) it is not broken down by the liver. Lisinopril is a competitive inhibitor of angiotensin-converting enzyme (ACE) and prevents the ...low sodium--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Common side effects of hydrochlorothiazide and lisinopril may include: cough; headache; dizziness; or. tired feeling. This is not a complete list of side effects and others may occur. Call your doctor …Reviews (515) Uses . This medication is used to treat high blood pressure. ... Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily.Dosage for Prinivil. Prinivil is available in doses of 5, 10, and 20 mg tablets for oral use. Hypertensive patients usually start with 10 mg once a day and are often increased to 20 mg. Patients with renal failure or who are on diuretics start at lower doses such as 2.5 to 5 mg.

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2.5 mg Tablets: White to off-white, round, unscored tablets, debossed with "C52" on one side and plain on other side. 5 mg Tablets: Reddish brown colored, over shaped tablets, debossed with ... 4. CONTRAINDICATIONS. Lisinopril is contraindicated in combination with a neprilysin inhibitor (e.g., sacubitril).Hydrochlorothiazide is a thiazide diuretic (water pill). It is used to help reduce the amount of water in the body by increasing the flow of urine. It may also be used for other conditions as determined by your doctor. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Capsule.kidney problems - swelling, urinating less, feeling tired or short of breath; or. liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common Zestril side effects may include: headache, dizziness; Condition: High Blood Pressure. Overall rating 2.0. Effectiveness. Ease of Use. Satisfaction. I am a busy author, aged 81, and also run an air bnb business out of my home. In November 2023 I was prescribed 10mg of Lisinopril for high bp. At the end of December I slipped and fell from my loft ladder and hurt my back. Jan 17, 2023 · Lisinopril is classified as an angiotensin-converting enzyme inhibitor and has been available for nearly three decades. Lisinopril has some key features that make it different from enalapril and captopril; 1) it has a long half-life, 2) it is hydrophilic, and 3) it is not broken down by the liver. Lisinopril is a competitive inhibitor of angiotensin-converting enzyme (ACE) and prevents the ... Lisinopril is an effective treatment for elderly patients with hypertension, congestive heart failure and acute myocardial infarction and has shown promising benefits in patients with diabetic nephropathy and cost saving compared with other ACE inhibitors in some markets. Lisinopril, the lysine analogue of enalaprilat, is a long-acting angiotensin converting enzyme (ACE) inhibitor which is ...Lisinopril is a white to off-white, crystalline powder, with a molecular weight of 441.52. It is soluble in water, sparingly soluble in methanol, and practically insoluble in ethanol. Hydrochlorothiazide is 6-chloro-3,4-dihydro-2 H -1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its empirical formula is C 7 H 8 ClN 3 O 4 S 2 and its ...Lisinopril tablet USP is indicated for the treatment of hypertension in adult patients and pediatric patients 6 years of age and older to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of ...BP was 186/92 then Dr. prescribed 20mg Lisinopril & I quickly developed blurred vision, headaches, tiredness and a nagging dry cough. Dr. quickly lowered dosage to 10mg & had me take pill at night & symptoms decreased significantly. 14 months later after losing 32lbs, my dosage was again lowered to 5mg and “ALL” the above symptoms are gone.Falken tires have above average ratings, according to rankings on 1010Tires.com. There are 13 Falken tires with reviews on the site, and the rating scores range from 3.7 stars out ... ….

Common side effects of hydrochlorothiazide and lisinopril may include: cough; headache; dizziness; or. tired feeling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Hydrochlorothiazide / lisinopril side effects (more ...Dosage for Prinivil. Prinivil is available in doses of 5, 10, and 20 mg tablets for oral use. Hypertensive patients usually start with 10 mg once a day and are often increased to 20 mg. Patients with renal failure or who are on diuretics start at lower doses such as 2.5 to 5 mg.The answer for how long lisinopril can stay in the system depends on many factors, including the dosage and whether one has been taking the drug for a short or long period of time. As a rule, most medical drugs taken will pass through the body within a few days or within a week, although there are exceptions.So lisinopril works because it blocks the conversion of angiotensin one to angiotensin two, it increases renin levels and it decreases aldosterone leading two VA dilation. We use lisinopril for the treatment of hypertension, as well as for the management of congestive heart failure. So ACE inhibitors in general are known for the side effect of ...In general, lisinopril has positive effects on the kidneys. But in some cases, lisinopril can affect how well your kidneys work. Fortunately, these effects are usually reversible. Your kidneys are responsible for filtering out toxins and waste from your blood. But when there isn’t enough blood flow, they aren’t able to do this job as well.Rated for Hypertension Report. Been taking 40 mg Lisinopril Lisinopri, 25 mg HCTZ and 25 mg Atenolol for hypertension for almost 2 yrs. Developed severe low sodium and potassium levels and ended up in the hospital for 3 days. Blood pressure was extremely low. Was temporarily taken off all BP meds.Find 4305 user ratings and reviews for Lisinopril Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfactionSep 11, 2023 · Three people share their experiences of taking lisinopril (Zestril), a medication that lowers blood pressure and treats heart failure. Learn about the benefits, side effects, and dosage of lisinopril from their stories. The answer for how long lisinopril can stay in the system depends on many factors, including the dosage and whether one has been taking the drug for a short or long period of time. As a rule, most medical drugs taken will pass through the body within a few days or within a week, although there are exceptions.Apr 1, 2024 · But lisinopril 20 mg decreased systolic blood pressure by about 14 points, and lisinopril 80 mg decreased it by about 20 points. Besides this small study, most of the available research we have is on lisinopril 10 mg. Research indicates that lisinopril 10 mg once daily may decrease your systolic blood pressure by about 8 points. Lisinopril reviews, Present review article determine the analytical methods for the quantitative determinations of lisinopril (ACE Inhibitor) by UV spectrophotometery and High-Performance Liquid chromatography., Lisinopril is well tolerated and may prove to be a useful prophylactic agent for migraine if the results of this study can be confirmed. Lisinopril Placebo Mean % reduction (95% CI), lisinopril, an inhibitor of the enzyme conversion. This enzyme is a naturally occurring substance in the body, causing a contraction of the arteries which increases blood pressure and heart fatigue; hydrochlorothiazide, a diuretic whose chemical structure is similar to that of sulfonamides. Its action strengthens that of lisinopril., Lisinopril is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure and to improve survival after a heart attack. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily., Ratings & Reviews: Lisinopril has an average rating of 5.0 out of 10 from a total of 625 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 43% reported a negative effect. Losartan has an average rating of 4.5 out of 10 from a total of 569 ratings on Drugs.com. 26% of reviewers reported a positive effect, while 49% ..., So lisinopril works because it blocks the conversion of angiotensin one to angiotensin two, it increases renin levels and it decreases aldosterone leading two VA dilation. We use lisinopril for the treatment of hypertension, as well as for the management of congestive heart failure. So ACE inhibitors in general are known for the side effect of ..., The news from your HVAC repairman that you need a new furnace is definitely not a welcome experience. Use this guide to find the top reviewed Bryant furnaces when replacing your fu..., Lisinopril in paediatric medicine: a retrospective chart review of long-term treatment in children., Raes A,Malfait F,Van Aken S,France A,Donckerwolcke R,Vande Walle J,, Journal of the renin-angiotensin-aldosterone system : JRAAS, 2007 Mar [PubMed PMID: 17487821], 25 Apr 2022 ... It is important to review these blood pressure medications with a doctor. Due to their possible side effects and drug interactions, one ..., Apr 1, 2024 · But lisinopril 20 mg decreased systolic blood pressure by about 14 points, and lisinopril 80 mg decreased it by about 20 points. Besides this small study, most of the available research we have is on lisinopril 10 mg. Research indicates that lisinopril 10 mg once daily may decrease your systolic blood pressure by about 8 points. , Apr 11, 2024 · Follow all instructions closely. Take with or without food. Take lisinopril and hydrochlorothiazide at the same time of day. Keep taking lisinopril and hydrochlorothiazide as you have been told by your doctor or other health care provider, even if you feel well. This medicine may cause you to pass urine more often. , Lisinopril is a prescription drug used to treat high blood pressure and heart failure. It belongs to a class of drugs called ACE inhibitors that relax the blood vessels …, Lisinopril is an effective treatment for elderly patients with hypertension, congestive heart failure and acute myocardial infarction and has shown promising benefits in patients with diabetic nephropathy and cost saving compared with other ACE inhibitors in some markets. Lisinopril, the lysine analogue of enalaprilat, is a long-acting angiotensin converting enzyme (ACE) inhibitor which is ..., These common side effects of lisinopril happen in more than 1 in 100 people. Talk to your doctor or pharmacist if these side effects bother you or do not go away: A dry, tickly cough that does not get better. Feeling dizzy or lightheaded, especially when you stand up or sit up quickly. Headaches. Being sick (vomiting), Find 515 user ratings and reviews for Lisinopril-hydrochlorothiazide Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction, Lisinopril is a prescription drug for high blood pressure, heart failure, and other conditions. Learn about its benefits, risks, interactions, dosage, and how to take it safely., Dec 19, 2022 · Lisinopril oral tablet is a generic prescription drug used for hypertension, heart failure, and heart attack. ... The insurance company will review the prior authorization request and decide if ... , Find 4305 user ratings and reviews for Lisinopril Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction, Common Prinivil side effects may include: headache, dizziness; low blood pressure, cough; or. chest pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Prinivil side effects (more detail), Lisinopril for Coronary Artery Disease User Reviews. Brand names: Zestril, Prinivil, Qbrelis. Lisinopril has an average rating of 3.7 out of 10 from a total of 3 reviews for the off-label treatment of Coronary Artery Disease. 0% of reviewers reported a positive experience, while 67% reported a negative experience., Lisinopril is used to treat high blood pressure. By lowering high blood pressure Lisinopril helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure . Another use of Lisinopril is to improve survival after a heart attack. Dosing and administration: This addresses the generic form of Lisinopril., Tablets and oral liquid medicine. Lisinopril belongs to a class of medicines called angiotensin-converting enzyme inhibitors, or ACE inhibitors. It is prescribed for a number of different reasons. You may have been prescribed it to reduce high blood pressure (hypertension), or to treat heart failure, or to protect your heart and blood vessels ..., Ratings & Reviews: Lisinopril has an average rating of 5.0 out of 10 from a total of 625 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 43% reported a negative effect. Losartan has an average rating of 4.5 out of 10 from a total of 569 ratings on Drugs.com. 26% of reviewers reported a positive effect, while 49% ..., 5 Nov 2022 ... In yet another study on patients with migraines, those taking Lisinopril (compared to taking nothing) experienced 20% fewer hours of headaches ..., Signs of a high potassium level like a heartbeat that does not feel normal; change in thinking clearly and with logic; feeling weak, lightheaded, or dizzy; feel like passing out; numbness or tingling; or shortness of breath . Very bad dizziness or passing out. Cough that does not go away. Very bad belly pain., depression, nausea, vomiting, diarrhea, upset stomach, and. mild skin itching or rash. Tell your doctor if you have unlikely but serious side effects of Zestril including: fainting, symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat, weak pulse, tingly feeling),, The NCLEX exam is a critical step in becoming a licensed nurse. As an aspiring nurse, you need to be well-prepared for this challenging test. One effective way to prepare is by rev..., Learn how lisinopril works, its benefits and side effects, interactions, and tips for using it. Lisinopril is an ACE inhibitor used to treat high blood pressure, heart failure, …, 1. NAME OF THE MEDICINAL PRODUCT. LISINOPRIL (Teva) 5 mg, tablet LISINOPRIL (Teva) 10 mg, tablet LISINOPRIL (Teva) 20 mg, tablet. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION. Lisinopril (Teva) tablets come in three strengths and contain lisinopril dihydrate equivalent to. 5 mg, 10 mg or 20 mg lisinopril., Read comments and ratings on the side effects, benefits, and effectiveness of lisinopril oral, a medication for high blood pressure. See how other patients experienced cough, …, These common side effects of lisinopril happen in more than 1 in 100 people. Talk to your doctor or pharmacist if these side effects bother you or do not go away: A dry, tickly cough that does not get better. Feeling dizzy or lightheaded, especially when you stand up or sit up quickly. Headaches. Being sick (vomiting), After reading 15 to 25 of the Lisinopril reviews and knowing many of the symptoms are just like many I've experienced, over the past three years since I began this medication. I was on a bp medication prior to this one and I stopped it pretty soon after beginning it. I read the reviews about it and it was a blood pressure medication that hadn't ..., Apr 1, 2024 · But lisinopril 20 mg decreased systolic blood pressure by about 14 points, and lisinopril 80 mg decreased it by about 20 points. Besides this small study, most of the available research we have is on lisinopril 10 mg. Research indicates that lisinopril 10 mg once daily may decrease your systolic blood pressure by about 8 points.